Professor and Head DEPARTMENT OF NEUROSURGERY,NIMHANS Bangalore, India
Introduction: Pediatric dystonia (PD) has a significant negative impact on the growth and development of the child.
Methods: This study was done retrospectively to analyze functional outcomes in pediatric patients with dystonia who underwent deep brain stimulation
Results: In this retrospective analytical study, all the patients of age less than 18 years undergoing DBS for dystonia between 2012 and 2020 in a single center were analyzed and their functional outcomes were measured by the Burke–Fahn–Marsden-dystonia-rating-scale (BFMDRS).
Conclusion : A total of nine pediatric patients were included with a mean age of onset, duration of disease, and age at surgery being 5.75 years, 7.36 years, and 13.11 years respectively with a mean follow-up of 23.22 months. The mean pre-DBS motor score was 75.44 ± 23.53 which improved significantly at 6 months and 12 months follow up to 57.27 (p value 0.004) and 50.38 (p value < 0.001) respectively. Limbs sub-scores improved significantly at both the scheduled intervals. There was a significant improvement in disability at 1-year follow-up with significant improvement in feeding, dressing, and walking components. There was 27.34 % and 36.64 % improvement in dystonia with 17.37 % and 28.86 % reduction in disability at 6 months and 12 months respectively. There was a positive correlation between the absolute reduction of the motor score and improvement in disability of the patients at 6 months (rho = 0.865, p value 0.003).This is one of the largest series in literature
